Personal profile

Disciplinary Classification

MED/04

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Neoplasms Medicine & Life Sciences
Medulloblastoma Medicine & Life Sciences
Genes Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
Mutation Medicine & Life Sciences
T-Cell Leukemia Medicine & Life Sciences
Growth Medicine & Life Sciences
Thymocytes Medicine & Life Sciences

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Research Output 2002 2016

A threshold level of NFATc1 activity facilitates thymocyte differentiation and opposes notch-driven leukaemia development

SCREPANTI, I., TALORA, C., Knobeloch, K-P., Serfling, E., Maqbool, M. A., Avots, A., Ellenrieder, V., Klein-Hessling, S., Muhammad, K., Andrau, J-C., Rudolf, R., Patra, A. K. & Cauchy, P. 2016 In : Nature Communications. 7

Research output: Research - peer-reviewArticle

leukemias
notches
thresholds
Thymocytes
Leukemia
3 Citations

Inhibition of Hedgehog-dependent tumors and cancer stem cells by a newly identified naturally occurring chemotype

BOTTA, B., bernardi, F., D'ACQUARICA, I., DI MARCOTULLIO, L., INGALLINA, C., SCREPANTI, I., QUAGLIO, D., CANETTIERI, G., Infante, P., Gulino, A., Ghirga, F., Mori, M., Di Magno, L. & Alfonsi, R. 2016 In : Cell Death and Disease. 7, 9

Research output: Research - peer-reviewArticle

HhAntag691
Neoplastic Stem Cells
Neoplasms
Chalcone
Drug Resistance
18 Citations

In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors

MATTERA, R., DE SMAELE, E., MASUELLI, L., SCREPANTI, I., Di Stefano, E., Bei, R., Cucchi, D., Bonanno, E., Gulino, A., Fantini, M., Modesti, A., Orlandi, A., Frajese, G. V. & Benvenuto, M. 2016 In : Oncotarget. 7, 8, p. 9250-9270 21 p.

Research output: Research - peer-reviewArticle

HhAntag691
Hedgehogs
Oncogenes
Glioma
Breast Neoplasms
2 Citations

MicroRNAs-Proteomic Networks Characterizing Human Medulloblastoma-SLCs

PO, A., SCREPANTI, I., FERRETTI, E., Besharat, Z. M., Locatelli, F., Garg, N., Urbani, A., Ronci, M., Alfano, V., Catanzaro, G., Mastronuzzi, A., Miele, E., Carai, A. & Pieroni, L. 2016 In : STEM CELLS INTERNATIONAL. 2016, p. 1-10 10 p.

Research output: Research - peer-reviewArticle

Notch3 sustains CXCR4 expression in acute T cell lymphoblastic leukemia progression

ferrandino, F., CHECQUOLO, S., CAMPESE, A. F., GRAZIOLI, P., BERNARDINI, G., BELLAVIA, D., FELLI, M. P. & SCREPANTI, I. 2016 Host publication title not available. Vol. 61, p. S87-S87 1 p.

Research output: ResearchConference contribution