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Disciplinary Calssification

CHIM/08

Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Histone Deacetylase Inhibitors Medicine & Life Sciences
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Research Output 2004 2016

  • 2427 Citations
  • 26 h-Index
  • 79 Article
  • 2 Chapter
4 Citations

1,4-Dihydropyridines Active on the SIRT1/AMPK Pathway Ameliorate Skin Repair and Mitochondrial Function and Exhibit Inhibition of Proliferation in Cancer Cells

Valente, S. , Mellini, P. , Spallotta, F. , Carafa, V. , Nebbioso, A. , Polletta, L. , Carnevale, I. , Saladini, S. , Trisciuoglio, D. , Gabellini, C. , Tardugno, M. , Zwergel, C. , Cencioni, C. , Atlante, S. , Moniot, S. , Steegborn, C. , Budriesi, R. , Tafani, M. , Del Bufalo, D. , Altucci, L. & 2 others Gaetano, C. & Mai, A. 25 Feb 2016 In : Journal of Medicinal Chemistry. 59, 4, p. 1471-1491 21 p.

Research output: Contribution to journalArticle

Dihydropyridines
AMP-Activated Protein Kinases
Skin
Neoplasms
Sirtuins
12 Citations

Discovery of a Novel Inhibitor of Histone Lysine-Specific Demethylase 1A (KDM1A/LSD1) as Orally Active Antitumor Agent

Vianello, P., Botrugno, O. A., Cappa, A., Dal Zuffo, R., Dessanti, P., Mai, A., Marrocco, B., Mattevi, A., Meroni, G., Minucci, S., Stazi, G., Thaler, F., Trifiró, P., Valente, S., Villa, M., Varasi, M. & Mercurio, C. 25 Feb 2016 In : Journal of Medicinal Chemistry. 59, 4, p. 1501-1517 17 p.

Research output: Contribution to journalArticle

Histone Demethylases
Antineoplastic Agents
Leukemia
Tranylcypromine
Acute Promyelocytic Leukemia
2 Citations

Histone deacetylase inhibitors restore IL-10 expression in lipopolysaccharide-induced cell inflammation and reduce IL-1β and IL-6 production in breast silicone implant in C57BL/6J wild-type murine model

Di Liddo, R., Valente, S., Taurone, S., Zwergel, C., Marrocco, B., Turchetta, R., Conconi, M. T., Scarpa, C., Bertalot, T., Schrenk, S., Mai, A. & Artico, M. 18 Jan 2016 In : Autoimmunity. p. 1-11 11 p.

Research output: Contribution to journalArticle

Breast Implants
Histone Deacetylase Inhibitors
Silicones
Interleukin-10
Lipopolysaccharides
7 Citations

LSD1 inhibitors: a patent review (2010-2015)

Stazi, G., Zwergel, C., Valente, S. & Mai, A. 28 Mar 2016 In : Expert Opinion on Therapeutic Patents. p. 1-16 16 p.

Research output: Contribution to journalArticle

Lysine
Neoplasms
Virus Latency
Literature
Adipogenesis
10 Citations

A novel coumarin-quinone derivative SV37 inhibits CDC25 phosphatases, impairs proliferation, and induces cell death

Bana, E., Sibille, E., Valente, S., Cerella, C., Chaimbault, P., Kirsch, G., Dicato, M., Diederich, M. & Bagrel, D. 1 Mar 2015 In : Molecular Carcinogenesis. 54, 3, p. 229-241 13 p.

Research output: Contribution to journalArticle

Coumarins
Phosphoric Monoester Hydrolases
Cell Death
Neoplasms
Cell Cycle Proteins