Personal profile

Disciplinary Classification

CHIM/08

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 28 Similar Profiles
Histone Deacetylase Inhibitors Medicine & Life Sciences
Histone Deacetylases Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Epigenomics Medicine & Life Sciences
Cells Chemical Compounds
Apoptosis Medicine & Life Sciences

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Research Output 2003 2016

  • 2678 Citations
  • 26 h-Index
  • 81 Article
  • 2 Conference contribution
  • 1 Chapter
  • 1 Abstract
4 Citations

1,4-Dihydropyridines Active on the SIRT1/AMPK Pathway Ameliorate Skin Repair and Mitochondrial Function and Exhibit Inhibition of Proliferation in Cancer Cells

VALENTE, S. , saladini, S. , MAI, A. , TAFANI, M. , Spallotta, F. , Atlante, S. , Gaetano, C. , Carafa, V. , Gabellini, C. , Zwergel, C. , Altucci, L. , Nebbioso, A. , Tardugno, M. , Cencioni, C. , Carnevale, I. , Moniot, S. , Trisciuoglio, D. , Mellini, P. , Del Bufalo, D. , Budriesi, R. & 2 others Steegborn, C. & Polletta, L. 2016 In : Journal of Medicinal Chemistry. 59, 4, p. 1471-1491 21 p.

Research output: Research - peer-reviewArticle

AMP-Activated Protein Kinases
Skin
Neoplasms
1,4-dihydropyridine
Therapeutics
13 Citations

Discovery of a Novel Inhibitor of Histone Lysine-Specific Demethylase 1A (KDM1A/LSD1) as Orally Active Antitumor Agent

VALENTE, S., MAI, A., STAZI, G., Mattevi, A., Cappa, A., Dal Zuffo, R., Meroni, G., Mercurio, C., Trifiró, P., Villa, M., Varasi, M., Minucci, S., Vianello, P., Dessanti, P., Thaler, F., Botrugno, O. A. & Marrocco, B. 2016 In : Journal of Medicinal Chemistry.

Research output: Research - peer-reviewArticle

Histone Demethylases
Antineoplastic Agents
Leukemia
Tranylcypromine
Acute Promyelocytic Leukemia
3 Citations

Histone deacetylase inhibitors restore IL-10 expression in lipopolysaccharide-induced cell inflammation and reduce IL-1β and IL-6 production in breast silicone implant in C57BL/6J wild-type murine model

VALENTE, S., ARTICO, M., MAI, A., TURCHETTA, R., TAURONE, S., Conconi, M. T., Di Liddo, R., Schrenk, S., Zwergel, C., Bertalot, T., Marrocco, B. & Scarpa, C. 2016 In : Autoimmunity. 20, p. 1-11 11 p.

Research output: Research - peer-reviewArticle

Breast Implants
Histone Deacetylase Inhibitors
Silicones
Interleukin-10
Lipopolysaccharides
9 Citations

LSD1 inhibitors: A patent review (2010-2015)

VALENTE, S., MAI, A., STAZI, G. & Zwergel, C. 2016 In : Expert Opinion on Therapeutic Patents. 26, 5, p. 565-580 16 p.

Research output: Research - peer-reviewArticle

Lysine
Virus Diseases
Neoplasms
Therapeutics
Virus Latency
3 Citations

MC1568 inhibits HDAC6/8 activity and influenza A virus replication in lung epithelial cells: Role of Hsp90 acetylation

VALENTE, S., PALAMARA, A. T., NENCIONI, L., MARCOCCI, M. E., MAI, A., SIMONETTI, G., Panella, S., Celestino, I., Zwergel, C. & Li Puma, D. D. 2016 In : Future Medicinal Chemistry. 8, 17, p. 2017-2031 15 p.

Research output: Research - peer-reviewArticle

Influenza A virus
Acetylation
Virus Replication
Epithelial Cells
Lung